3-hydroxy-pyridine-2-carboxylic acid methyl ester

3-hydroxy-pyridine-2-carboxylic acid methyl ester - Names and Identifiers

Name	3-Hydroxy-2-pyridinecarboxylic acid methyl ester
Synonyms	3-HYDROXYPICOLINIC ACID METHYL ESTER methyl 3-hydroxypyridine-2-carboxylate METHYL 3-HYDROXYPYRIDINE-2-CARBOXYLATE 3-hydroxy-2-pyridinecarboxylicacidmethylester 3-Hydroxy-2-pyridinecarboxylic acid methyl ester 3-HYDROXY-PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER 3-hydroxy-pyridine-2-carboxylic acid methyl ester 2-Pyridinecarboxylicacid,3-hydroxy-,methylester(9CI) 3-Hydroxy-pyridine-2-carboxylic acid methyl ester HCl 3-hydroxy-2-pyridinecarboxylic acid methyl ester hydrochloride
CAS	62733-99-7
InChI	InChI=1/C7H7NO3/c1-11-7(10)6-5(9)3-2-4-8-6/h2-4,9H,1H3

3-hydroxy-pyridine-2-carboxylic acid methyl ester - Physico-chemical Properties

Molecular Formula	C7H7NO3
Molar Mass	153.14
Density	1.287±0.06 g/cm3(Predicted)
Melting Point	75.0 to 79.0 °C
Boling Point	340.6±22.0 °C(Predicted)
Flash Point	159.8°C
Vapor Presure	4.3E-05mmHg at 25°C
pKa	4.45±0.10(Predicted)
Storage Condition	Inert atmosphere,Room Temperature
Refractive Index	1.551

3-hydroxy-pyridine-2-carboxylic acid methyl ester - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36 - Irritating to the eyes
Safety Description	26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

3-hydroxy-pyridine-2-carboxylic acid methyl ester - Introduction

Acid methyl ester is an organic compound with the chemical formula C7H7NO3. It is a colorless to pale yellow liquid with the characteristic properties of pyridine and hydroxyl groups. The following is a detailed introduction to the nature, use, formulation and safety information of acid ester:

Nature:
1. appearance: colorless to light yellow liquid.
2. Molecular weight: 161.14g/mol.
3. melting point: no obvious melting point.
4. Boiling point: 290-295°C.
5. Density: 1.231 g/mL.
6. Solubility: Soluble in organic solvents, such as alcohols and ethers.

Use:
1. chemical synthesis: acid methyl ester can be used in organic synthesis reactions as reagents or intermediates.
2. Drug research: It is a commonly used organic synthetic raw material, commonly used in the preparation of intermediates in the process of drug research and development.

Preparation Method:
The preparation method of acid methyl ester is as follows:
3-hydroxypyridine and methyl formate are reacted under appropriate conditions, and acid methyl ester is obtained through esterification reaction.

Safety Information:
1. acid methyl ester may be irritating to eyes and skin, so pay attention to protective measures during operation, such as wearing gloves and goggles.
2. when storing and handling acid methyl ester, keep away from fire and heat sources.
3. when using acid methyl ester, be sure to follow the relevant laboratory safety guidelines and operating procedures.

Please note that when using chemicals, it is important to follow correct safe operating procedures and operate under suitable laboratory conditions. When necessary, it is recommended to consult a professional chemist for more detailed and accurate information.

Last Update：2024-04-09 20:49:11